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DESCRIPTION
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DESCRIPTION
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Package: sctransform
Type: Package
Title: Variance Stabilizing Transformations for Single Cell UMI Data
Version: 0.4.1
Date: 2023-10-18
Authors@R: c(
person(given = "Christoph", family = "Hafemeister", email = "[email protected]", role = "aut", comment = c(ORCID = "0000-0001-6365-8254")),
person(given = "Saket", family = "Choudhary", email = "[email protected]", role = c("aut", "cre"), comment = c(ORCID = "0000-0001-5202-7633")),
person(given = "Rahul", family = "Satija", email = "[email protected]", role = "ctb", comment = c(ORCID = "0000-0001-9448-8833"))
)
Description: A normalization method for single-cell UMI count data using a
variance stabilizing transformation. The transformation is based on a
negative binomial regression model with regularized parameters. As part of the
same regression framework, this package also provides functions for
batch correction, and data correction. See Hafemeister and Satija (2019)
<doi:10.1186/s13059-019-1874-1>, and Choudhary and Satija (2022) <doi:10.1186/s13059-021-02584-9>
for more details.
URL: https://github.com/satijalab/sctransform
BugReports: https://github.com/satijalab/sctransform/issues
License: GPL-3 | file LICENSE
Encoding: UTF-8
LazyData: true
Depends: R (>= 3.6.0)
LinkingTo: RcppArmadillo, Rcpp (>= 0.11.0)
SystemRequirements: C++17
Imports:
dplyr,
magrittr,
MASS,
Matrix (>= 1.5-0),
methods,
future.apply,
future,
ggplot2,
reshape2,
rlang,
gridExtra,
matrixStats
Suggests:
irlba,
testthat,
knitr
Enhances:
glmGamPoi
RoxygenNote: 7.2.3