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PureCLIP 1.3.0
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@skrakau skrakau released this 22 Feb 18:45
v1.3.0
0de8391

  • Extension to handle individual replicates (currently only two). Emission probability parameters are learned for each replicate separately. Joint emission probabilities are then used in the final HMM.

  • Added user option '-st' to choose alternative crosslink site scoring scheme, which is also used to compute scores for binding regions. For the called crosslink sites alternative scores are reported in column 7.

  • GLM to learn correlation between input control and target signals: added check and re-seeding to ensure that the expected value for the 'enriched' state remains greater than the expected value for the 'non-enriched' state across range of input fragment density values.

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